Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies

LukGH (LukAB) is a potent leukocidin of Staphylococcus aureus that lyses human phagocytic cells and is thought to contribute to immune evasion. Unlike the other bi-component leukocidins of S. aureus, LukGH forms a heterodimer before binding to its receptor, CD11b expressed on professional phagocytic...

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Publicado no:MAbs
Main Authors: Badarau, Adriana, Rouha, Harald, Malafa, Stefan, Battles, Michael B., Walker, Laura, Nielson, Nels, Dolezilkova, Ivana, Teubenbacher, Astrid, Banerjee, Srijib, Maierhofer, Barbara, Weber, Susanne, Stulik, Lukas, Logan, Derek T., Welin, Martin, Mirkina, Irina, Pleban, Clara, Zauner, Gerhild, Gross, Karin, Jägerhofer, Michaela, Magyarics, Zoltán, Nagy, Eszter
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058624/
https://ncbi.nlm.nih.gov/pubmed/27467113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1215791
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