Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH

The bi-component leukocidins of Staphylococcus aureus are important virulence factors that lyse human phagocytic cells and contribute to immune evasion. The γ-hemolysins (HlgAB and HlgCB) and Panton-Valentine leukocidin (PVL or LukSF) were shown to assemble from soluble subunits into membrane-bound...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Badarau, Adriana, Rouha, Harald, Malafa, Stefan, Logan, Derek T., Håkansson, Maria, Stulik, Lukas, Dolezilkova, Ivana, Teubenbacher, Astrid, Gross, Karin, Maierhofer, Barbara, Weber, Susanne, Jägerhofer, Michaela, Hoffman, David, Nagy, Eszter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281717/
https://ncbi.nlm.nih.gov/pubmed/25371205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598110
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