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The role of PHD2 mutations in the pathogenesis of erythrocytosis

The transcription of the erythropoietin (EPO) gene is tightly regulated by the hypoxia response pathway to maintain oxygen homeostasis. Elevations in serum EPO level may be reflected in an augmentation in the red cell mass, thereby causing erythrocytosis. Studies on erythrocytosis have provided insi...

詳細記述

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書誌詳細
出版年:Hypoxia (Auckl)
主要な著者: Gardie, Betty, Percy, Melanie J, Hoogewijs, David, Chowdhury, Rasheduzzaman, Bento, Celeste, Arsenault, Patrick R, Richard, Stéphane, Almeida, Helena, Ewing, Joanne, Lambert, Frédéric, McMullin, Mary Frances, Schofield, Christopher J, Lee, Frank S
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045058/
https://ncbi.nlm.nih.gov/pubmed/27774468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S54455
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