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The role of PHD2 mutations in the pathogenesis of erythrocytosis
The transcription of the erythropoietin (EPO) gene is tightly regulated by the hypoxia response pathway to maintain oxygen homeostasis. Elevations in serum EPO level may be reflected in an augmentation in the red cell mass, thereby causing erythrocytosis. Studies on erythrocytosis have provided insi...
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出版年: | Hypoxia (Auckl) |
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主要な著者: | , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Dove Medical Press
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045058/ https://ncbi.nlm.nih.gov/pubmed/27774468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S54455 |
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