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One more stem cell niche: how the sensitivity of chronic myeloid leukemia cells to imatinib mesylate is modulated within a “hypoxic” environment

This is a review (by no means comprehensive) of how the stem cell niche evolved from an abstract concept to a complex system, implemented with a number of experimental data at the cellular and molecular levels, including metabolic cues, on which we focused in particular. The concept was introduced i...

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Библиографические подробности
Опубликовано в: :Hypoxia (Auckl)
Главные авторы: Rovida, Elisabetta, Marzi, Ilaria, Cipolleschi, Maria Grazia, Dello Sbarba, Persio
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045050/
https://ncbi.nlm.nih.gov/pubmed/27774462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S51812
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