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Chronic myeloid leukaemia and hepatoblastoma: two cancer models to link metabolism to stem cells.

Low oxygen tension is a critical aspect of the stem cell niche where stem cells are long-term maintained. In physiologically hypoxic stem cell niches, low oxygen tension restrains the clonal expansion of stem cells without blocking their cycling, thereby contributing substantially to favour their se...

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Autors principals: Persio eDello Sbarba, Maria Grazia eCipolleschi, Ilaria eMarzi, Elisabetta eRovida
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016-04-01
Col·lecció:Frontiers in Oncology
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Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00095/full
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