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Chronic myeloid leukaemia and hepatoblastoma: two cancer models to link metabolism to stem cells.
Low oxygen tension is a critical aspect of the stem cell niche where stem cells are long-term maintained. In physiologically hypoxic stem cell niches, low oxygen tension restrains the clonal expansion of stem cells without blocking their cycling, thereby contributing substantially to favour their se...
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Autors principals: | , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Frontiers Media S.A.
2016-04-01
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Col·lecció: | Frontiers in Oncology |
Matèries: | |
Accés en línia: | http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00095/full |
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