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One more stem cell niche: how the sensitivity of chronic myeloid leukemia cells to imatinib mesylate is modulated within a “hypoxic” environment

This is a review (by no means comprehensive) of how the stem cell niche evolved from an abstract concept to a complex system, implemented with a number of experimental data at the cellular and molecular levels, including metabolic cues, on which we focused in particular. The concept was introduced i...

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Detalhes bibliográficos
Publicado no:Hypoxia (Auckl)
Main Authors: Rovida, Elisabetta, Marzi, Ilaria, Cipolleschi, Maria Grazia, Dello Sbarba, Persio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045050/
https://ncbi.nlm.nih.gov/pubmed/27774462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S51812
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