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Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model

Most common male reproductive disorders are linked to lower testosterone exposure in fetal life, although the factors responsible for suppressing fetal testosterone remain largely unknown. Protracted use of acetaminophen during pregnancy is associated with increased risk of cryptorchidism in sons, b...

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Détails bibliographiques
Publié dans:Sci Transl Med
Auteurs principaux: van den Driesche, Sander, Macdonald, Joni, Anderson, Richard A., Johnston, Zoe C., Chetty, Tarini, Smith, Lee B., Mckinnell, Chris, Dean, Afshan, Homer, Natalie Z., Jorgensen, Anne, Camacho-Moll, Maria-Elena, Sharpe, Richard M., Mitchell, Rod T.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044981/
https://ncbi.nlm.nih.gov/pubmed/25995226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa4097
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