Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts

In rodents, in utero exposure to exogenous estrogens including diethylstilboestrol (DES) results in major suppression of steroidogenesis in fetal testes. Whether similar effects occur in the human fetal testis is equivocal. Based on the results of the rodent studies, we hypothesised that exposure of...

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Hauptverfasser: Mitchell, Rod T., Sharpe, Richard M., Anderson, Richard A., McKinnell, Chris, Macpherson, Sheila, Smith, Lee B., Wallace, W. Hamish B., Kelnar, Christopher J. H., van den Driesche, Sander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631175/
https://ncbi.nlm.nih.gov/pubmed/23620786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061726
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