Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts

In rodents, in utero exposure to exogenous estrogens including diethylstilboestrol (DES) results in major suppression of steroidogenesis in fetal testes. Whether similar effects occur in the human fetal testis is equivocal. Based on the results of the rodent studies, we hypothesised that exposure of...

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Autori principali: Mitchell, Rod T., Sharpe, Richard M., Anderson, Richard A., McKinnell, Chris, Macpherson, Sheila, Smith, Lee B., Wallace, W. Hamish B., Kelnar, Christopher J. H., van den Driesche, Sander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631175/
https://ncbi.nlm.nih.gov/pubmed/23620786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061726
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