Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts

In rodents, in utero exposure to exogenous estrogens including diethylstilboestrol (DES) results in major suppression of steroidogenesis in fetal testes. Whether similar effects occur in the human fetal testis is equivocal. Based on the results of the rodent studies, we hypothesised that exposure of...

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Main Authors: Mitchell, Rod T., Sharpe, Richard M., Anderson, Richard A., McKinnell, Chris, Macpherson, Sheila, Smith, Lee B., Wallace, W. Hamish B., Kelnar, Christopher J. H., van den Driesche, Sander
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631175/
https://ncbi.nlm.nih.gov/pubmed/23620786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061726
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