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Comparative Effects of Di(n-Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts

BACKGROUND: Phthalate exposure induces germ cell effects in the fetal rat testis. Although experimental models have shown that the human fetal testis is insensitive to the steroidogenic effects of phthalates, the effects on germ cells have been less explored. OBJECTIVES: We sought to identify the ef...

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Bibliographic Details
Published in:Environ Health Perspect
Main Authors: van den Driesche, Sander, McKinnell, Chris, Calarrão, Ana, Kennedy, Laura, Hutchison, Gary R., Hrabalkova, Lenka, Jobling, Matthew S., Macpherson, Sheila, Anderson, Richard A., Sharpe, Richard M., Mitchell, Rod T.
Format: Artigo
Language:Inglês
Published: NLM-Export 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348744/
https://ncbi.nlm.nih.gov/pubmed/25514601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408248
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