Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences

Analgesics which affect prostaglandin (PG) pathways are used by most pregnant women. As germ cells (GC) undergo developmental and epigenetic changes in fetal life and are PG targets, we investigated if exposure of pregnant rats to analgesics (indomethacin or acetaminophen) affected GC development an...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Dean, Afshan, van den Driesche, Sander, Wang, Yili, McKinnell, Chris, Macpherson, Sheila, Eddie, Sharon L., Kinnell, Hazel, Hurtado-Gonzalez, Pablo, Chambers, Tom J., Stevenson, Kerrie, Wolfinger, Elke, Hrabalkova, Lenka, Calarrao, Ana, Bayne, Rosey AL, Hagen, Casper P., Mitchell, Rod T., Anderson, Richard A., Sharpe, Richard M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728385/
https://ncbi.nlm.nih.gov/pubmed/26813099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19789
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы