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Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency

The UL133–138 locus present in clinical strains of human cytomegalovirus (HCMV) encodes proteins required for latency and reactivation in CD34(+) hematopoietic progenitor cells and virion maturation in endothelial cells. The encoded proteins form multiple homo- and hetero-interactions and localize w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Lee, Song Hee, Caviness, Katie, Albright, Emily R., Lee, Jeong-Hee, Gelbmann, Christopher B., Rak, Mike, Goodrum, Felicia, Kalejta, Robert F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044833/
https://ncbi.nlm.nih.gov/pubmed/27512069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01547-16
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