Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency

The UL133–138 locus present in clinical strains of human cytomegalovirus (HCMV) encodes proteins required for latency and reactivation in CD34(+) hematopoietic progenitor cells and virion maturation in endothelial cells. The encoded proteins form multiple homo- and hetero-interactions and localize w...

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Bibliographic Details
Published in:J Virol
Main Authors: Lee, Song Hee, Caviness, Katie, Albright, Emily R., Lee, Jeong-Hee, Gelbmann, Christopher B., Rak, Mike, Goodrum, Felicia, Kalejta, Robert F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044833/
https://ncbi.nlm.nih.gov/pubmed/27512069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01547-16
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