Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency

The UL133–138 locus present in clinical strains of human cytomegalovirus (HCMV) encodes proteins required for latency and reactivation in CD34(+) hematopoietic progenitor cells and virion maturation in endothelial cells. The encoded proteins form multiple homo- and hetero-interactions and localize w...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lee, Song Hee, Caviness, Katie, Albright, Emily R., Lee, Jeong-Hee, Gelbmann, Christopher B., Rak, Mike, Goodrum, Felicia, Kalejta, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044833/
https://ncbi.nlm.nih.gov/pubmed/27512069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01547-16
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