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Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency

The UL133–138 locus present in clinical strains of human cytomegalovirus (HCMV) encodes proteins required for latency and reactivation in CD34(+) hematopoietic progenitor cells and virion maturation in endothelial cells. The encoded proteins form multiple homo- and hetero-interactions and localize w...

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Publicat a:J Virol
Autors principals: Lee, Song Hee, Caviness, Katie, Albright, Emily R., Lee, Jeong-Hee, Gelbmann, Christopher B., Rak, Mike, Goodrum, Felicia, Kalejta, Robert F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044833/
https://ncbi.nlm.nih.gov/pubmed/27512069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01547-16
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