Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis

BACKGROUND: A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Genomics
Egile Nagusiak: Qiu, Si, Li, Wenhui, Xiong, Heng, Liu, Dongbing, Bai, Yali, Wu, Kui, Zhang, Xiuqing, Yang, Huanming, Ma, Kun, Hou, Yong, Li, Bo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043600/
https://ncbi.nlm.nih.gov/pubmed/27687780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3115-2
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