Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis

BACKGROUND: A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis....

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Qiu, Si, Li, Wenhui, Xiong, Heng, Liu, Dongbing, Bai, Yali, Wu, Kui, Zhang, Xiuqing, Yang, Huanming, Ma, Kun, Hou, Yong, Li, Bo
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043600/
https://ncbi.nlm.nih.gov/pubmed/27687780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3115-2
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