Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis

BACKGROUND: A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Genomics
Päätekijät: Qiu, Si, Li, Wenhui, Xiong, Heng, Liu, Dongbing, Bai, Yali, Wu, Kui, Zhang, Xiuqing, Yang, Huanming, Ma, Kun, Hou, Yong, Li, Bo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043600/
https://ncbi.nlm.nih.gov/pubmed/27687780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3115-2
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