Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis

BACKGROUND: A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis....

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Qiu, Si, Li, Wenhui, Xiong, Heng, Liu, Dongbing, Bai, Yali, Wu, Kui, Zhang, Xiuqing, Yang, Huanming, Ma, Kun, Hou, Yong, Li, Bo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043600/
https://ncbi.nlm.nih.gov/pubmed/27687780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3115-2
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