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The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs

Once every menstrual cycle, eggs are ovulated into the oviduct where they await fertilization. The ovulated eggs are arrested in metaphase of the second meiotic division, and only complete meiosis upon fertilization. It is crucial that the maintenance of metaphase arrest is tightly controlled, becau...

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Bibliografske podrobnosti
izdano v:Open Biol
Main Authors: Pasternak, Michał, Pfender, Sybille, Santhanam, Balaji, Schuh, Melina
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043581/
https://ncbi.nlm.nih.gov/pubmed/27605379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160184
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