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The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs

Once every menstrual cycle, eggs are ovulated into the oviduct where they await fertilization. The ovulated eggs are arrested in metaphase of the second meiotic division, and only complete meiosis upon fertilization. It is crucial that the maintenance of metaphase arrest is tightly controlled, becau...

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Pubblicato in:Open Biol
Autori principali: Pasternak, Michał, Pfender, Sybille, Santhanam, Balaji, Schuh, Melina
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043581/
https://ncbi.nlm.nih.gov/pubmed/27605379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160184
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