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Deadenylation of maternal mRNAs mediated by miR-427 in Xenopus laevis embryos

We show that microRNA-427 (miR-427) mediates the rapid deadenylation of maternal mRNAs after the midblastula transition (MBT) of Xenopus laevis embryogenesis. By MBT, the stage when the embryonic cell cycle is remodeled and zygotic transcription of mRNAs is initiated, each embryo has accumulated ∼10...

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Bibliografiske detaljer
Main Authors: Lund, Elsebet, Liu, Mingzhu, Hartley, Rebecca S., Sheets, Michael D., Dahlberg, James E.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779678/
https://ncbi.nlm.nih.gov/pubmed/19854872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1882009
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