Deadenylation of maternal mRNAs mediated by miR-427 in Xenopus laevis embryos

We show that microRNA-427 (miR-427) mediates the rapid deadenylation of maternal mRNAs after the midblastula transition (MBT) of Xenopus laevis embryogenesis. By MBT, the stage when the embryonic cell cycle is remodeled and zygotic transcription of mRNAs is initiated, each embryo has accumulated ∼10...

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Bibliographic Details
Main Authors: Lund, Elsebet, Liu, Mingzhu, Hartley, Rebecca S., Sheets, Michael D., Dahlberg, James E.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779678/
https://ncbi.nlm.nih.gov/pubmed/19854872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1882009
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