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HNSCC cells resistant to EGFR pathway inhibitors are hypermutated and sensitive to DNA damaging substances
Despite remarkable successes with targeted therapies in the treatment of cancer, resistance can occur which limits the clinical outcome. In this study, we generated and characterized resistant cell clones derived from two different head and neck squamous cell carcinoma (HNSCC) cell lines (Cal27, UD-...
Gardado en:
| Publicado en: | Am J Cancer Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
e-Century Publishing Corporation
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5043106/ https://ncbi.nlm.nih.gov/pubmed/27725902 |
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