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Selective inhibition of EGFR downstream signaling reverses the irradiation-enhanced migration of HNSCC cells

Irradiation, which is one of the standard therapies used to treat squamous cell carcinoma of the head and neck (HNSCC), has been linked to enhanced tumor migration in carcinomas. In this study, we demonstrated that irradiation induced the phosphorylation of AKT, p38 MAPK and ERK. The combined activa...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Schuettler, Dominik, Piontek, Guido, Wirth, Markus, Haller, Bernhard, Reiter, Rudolf, Brockhoff, Gero, Pickhard, Anja
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633896/
https://ncbi.nlm.nih.gov/pubmed/26609474
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