Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation

BACKGROUND: The epidermal growth factor receptor (EGFR) is an important regulator of cell growth and survival, and is highly variable in tumor cells. The most prevalent variation of the EGFR extracellular domain is the EGFR variant III (EGFRvIII). Some studies imply that EGFRvIII may be responsible...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Koch, Dominik Thomas, Pickhard, Anja, Gebel, Lena, Buchberger, Anna Maria S., Bas, Murat, Mogler, Carolin, Reiter, Rudolf, Piontek, Guido, Wirth, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464818/
https://ncbi.nlm.nih.gov/pubmed/28427242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15949
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