Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

AIMS/HYPOTHESIS: Human pancreatic beta cells may be complicit in their own demise in type 1 diabetes, but how this occurs remains unclear. One potentially contributing factor is hyperexpression of HLA class I antigens. This was first described approximately 30 years ago, but has never been fully cha...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Richardson, Sarah J., Rodriguez-Calvo, Teresa, Gerling, Ivan C., Mathews, Clayton E., Kaddis, John S., Russell, Mark A., Zeissler, Marie, Leete, Pia, Krogvold, Lars, Dahl-Jørgensen, Knut, von Herrath, Matthias, Pugliese, Alberto, Atkinson, Mark A., Morgan, Noel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042874/
https://ncbi.nlm.nih.gov/pubmed/27506584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4067-4
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