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Abnormal islet sphingolipid metabolism in type 1 diabetes
AIMS/HYPOTHESIS: Sphingolipids play important roles in beta cell physiology, by regulating proinsulin folding and insulin secretion and in controlling apoptosis, as studied in animal models and cell cultures. Here we investigate whether sphingolipid metabolism may contribute to the pathogenesis of h...
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| Veröffentlicht in: | Diabetologia |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445476/ https://ncbi.nlm.nih.gov/pubmed/29671030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4614-2 |
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