Abnormal islet sphingolipid metabolism in type 1 diabetes

AIMS/HYPOTHESIS: Sphingolipids play important roles in beta cell physiology, by regulating proinsulin folding and insulin secretion and in controlling apoptosis, as studied in animal models and cell cultures. Here we investigate whether sphingolipid metabolism may contribute to the pathogenesis of h...

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Bibliografski detalji
Izdano u:Diabetologia
Glavni autori: Holm, Laurits J., Krogvold, Lars, Hasselby, Jane P., Kaur, Simranjeet, Claessens, Laura A., Russell, Mark A., Mathews, Clayton E., Hanssen, Kristian F., Morgan, Noel G., Koeleman, Bobby P. C., Roep, Bart O., Gerling, Ivan C., Pociot, Flemming, Dahl-Jørgensen, Knut, Buschard, Karsten
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445476/
https://ncbi.nlm.nih.gov/pubmed/29671030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4614-2
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