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One in Ten CD8(+) Cells in the Pancreas of Living Individuals With Recent-Onset Type 1 Diabetes Recognizes the Preproinsulin Epitope PPI(15-24)
In type 1 diabetes (T1D), a lifelong autoimmune disease, T cells infiltrate the islets and the exocrine pancreas in high numbers. CD8(+) T cells are the main cell type found in the insulitic lesion, and CD8(+) T cells reactive against β-cell antigens have been detected in peripheral blood and in the...
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| Опубликовано в: : | Diabetes |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Diabetes Association
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7897350/ https://ncbi.nlm.nih.gov/pubmed/33414250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0908 |
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