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Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes

Type 1 diabetes (T1D) results from a complex interplay between genetic susceptibility and environmental factors that have been implicated in the pathogenesis of disease both as triggers and potentiators of β-cell destruction. CD8 T cells are the main cell type found in human islets, and they have be...

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Detalhes bibliográficos
Main Authors: Rodriguez-Calvo, Teresa, Ekwall, Olov, Amirian, Natalie, Zapardiel-Gonzalo, Jose, von Herrath, Matthias G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207385/
https://ncbi.nlm.nih.gov/pubmed/24947367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0549
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