Alpha Cells, The Main Source of IL-1β in Human Pancreas

Interleukin-1β (IL-1β) is known to trigger beta cell dysfunction in vitro and could potentially play a role during the pathogenesis of type 1 diabetes and type 2 diabetes. However, several clinical trials attempting to block IL-1β function have had minimal success. We therefore reinvestigated local...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Anquetil, Florence, Sabouri, Somayeh, Thivolet, Charles, Rodriguez-Calvo, Teresa, Zapardiel-Gonzalo, Jose, Amirian, Natalie, Schneider, Darius, Castillo, Ericka, Lajevardi, Yasaman, von Herrath, Matthias G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507672/
https://ncbi.nlm.nih.gov/pubmed/28325643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2017.03.006
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