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Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection
We reported that arginase 2 (ARG2) deletion results in increased gastritis and decreased bacterial burden during Helicobacter pylori infection in mice. Our studies implicated a potential role for inducible nitric oxide (NO) synthase (NOS2), as Arg2(−/−) mice exhibited increased NOS2 levels in gastri...
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| Udgivet i: | Amino Acids |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042810/ https://ncbi.nlm.nih.gov/pubmed/27074721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2231-2 |
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