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Arginase II Restricts Host Defense to Helicobacter pylori by Attenuating Inducible Nitric Oxide Synthase Translation in Macrophages

Helicobacter pylori infection of the stomach causes peptic ulcer disease and gastric cancer. Despite eliciting a vigorous immune response, the bacterium persists for the life of the host. An important antimicrobial mechanism is the production of NO derived from inducible NO synthase (iNOS). We have...

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Detalhes bibliográficos
Main Authors: Lewis, Nuruddeen D., Asim, Mohammad, Barry, Daniel P., Singh, Kshipra, de Sablet, Thibaut, Boucher, Jean-Luc, Gobert, Alain P., Chaturvedi, Rupesh, Wilson, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841360/
https://ncbi.nlm.nih.gov/pubmed/20097867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902436
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