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Arginase II Restricts Host Defense to Helicobacter pylori by Attenuating Inducible Nitric Oxide Synthase Translation in Macrophages

Helicobacter pylori infection of the stomach causes peptic ulcer disease and gastric cancer. Despite eliciting a vigorous immune response, the bacterium persists for the life of the host. An important antimicrobial mechanism is the production of NO derived from inducible NO synthase (iNOS). We have...

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Bibliografische gegevens
Hoofdauteurs: Lewis, Nuruddeen D., Asim, Mohammad, Barry, Daniel P., Singh, Kshipra, de Sablet, Thibaut, Boucher, Jean-Luc, Gobert, Alain P., Chaturvedi, Rupesh, Wilson, Keith T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841360/
https://ncbi.nlm.nih.gov/pubmed/20097867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902436
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