Genome Analysis of Osteosarcoma Progression Samples Identifies FGFR1 Overexpression as a Potential Treatment Target and CHM as a Candidate Tumor Suppressor Gene

Osteosarcoma (OS) is the most common primary malignant tumor of bone, showing complex chromosomal rearrangements but with few known consistent changes. Deeper biological understanding is crucial to find new therapies to improve patient survival. We have sequenced the whole exome of two primary tumor...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Barøy, Tale, Chilamakuri, Chandra S. R., Lorenz, Susanne, Sun, Jinchang, Bruland, Øyvind S., Myklebost, Ola, Meza-Zepeda, Leonardo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042545/
https://ncbi.nlm.nih.gov/pubmed/27685995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163859
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