Multi-Center Evaluation of the Fully Automated PCR-Based Idylla(™) KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer

Since the advent of monoclonal antibodies against epidermal growth factor receptor (EGFR) in colorectal cancer therapy, the determination of RAS mutational status is needed for therapeutic decision-making. Most prevalent in colorectal cancer are KRAS exon 2 mutations (40% prevalence); lower prevalen...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Solassol, Jérôme, Vendrell, Julie, Märkl, Bruno, Haas, Christian, Bellosillo, Beatriz, Montagut, Clara, Smith, Matthew, O’Sullivan, Brendan, D’Haene, Nicky, Le Mercier, Marie, Grauslund, Morten, Melchior, Linea Cecilie, Burt, Emma, Cotter, Finbarr, Stieber, Daniel, Schmitt, Fernando de Lander, Motta, Valentina, Lauricella, Calogero, Colling, Richard, Soilleux, Elizabeth, Fassan, Matteo, Mescoli, Claudia, Collin, Christine, Pagès, Jean-Christophe, Sillekens, Peter
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042411/
https://ncbi.nlm.nih.gov/pubmed/27685259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163444
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