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Cell-Free Systems Based on CHO Cell Lysates: Optimization Strategies, Synthesis of “Difficult-to-Express” Proteins and Future Perspectives

Nowadays, biotechnological processes play a pivotal role in target protein production. In this context, Chinese Hamster Ovary (CHO) cells are one of the most prominent cell lines for the expression of recombinant proteins and revealed as a safe host for nearly 40 years. Nevertheless, the major bottl...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Thoring, Lena, Wüstenhagen, Doreen A., Borowiak, Maria, Stech, Marlitt, Sonnabend, Andrei, Kubick, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042383/
https://ncbi.nlm.nih.gov/pubmed/27684475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163670
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