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Cell-Free Systems Based on CHO Cell Lysates: Optimization Strategies, Synthesis of “Difficult-to-Express” Proteins and Future Perspectives

Nowadays, biotechnological processes play a pivotal role in target protein production. In this context, Chinese Hamster Ovary (CHO) cells are one of the most prominent cell lines for the expression of recombinant proteins and revealed as a safe host for nearly 40 years. Nevertheless, the major bottl...

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書目詳細資料
發表在:PLoS One
Main Authors: Thoring, Lena, Wüstenhagen, Doreen A., Borowiak, Maria, Stech, Marlitt, Sonnabend, Andrei, Kubick, Stefan
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042383/
https://ncbi.nlm.nih.gov/pubmed/27684475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163670
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