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High-yield cell-free synthesis of human EGFR by IRES-mediated protein translation in a continuous exchange cell-free reaction format

Cell-free protein synthesis systems derived from eukaryotic sources often provide comparatively low amounts of several μg per ml of de novo synthesized membrane protein. In order to overcome this, we herein demonstrate the high-yield cell-free synthesis of the human EGFR in a microsome-containing sy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Quast, Robert B., Sonnabend, Andrei, Stech, Marlitt, Wüstenhagen, Doreen A., Kubick, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960648/
https://ncbi.nlm.nih.gov/pubmed/27456041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30399
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