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High-yield production of “difficult-to-express” proteins in a continuous exchange cell-free system based on CHO cell lysates

Cell-free protein synthesis (CFPS) represents a promising technology for efficient protein production targeting especially so called “difficult-to-express” proteins whose synthesis is challenging in conventional in vivo protein production platforms. Chinese hamster ovary (CHO) cells are one of the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Thoring, Lena, Dondapati, Srujan K., Stech, Marlitt, Wüstenhagen, Doreen A., Kubick, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601898/
https://ncbi.nlm.nih.gov/pubmed/28916746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12188-8
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