TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway

Targeting angiogenesis is considered a promising therapy for cancer. Besides curtailing soluble factor mediated tumor angiogenesis, understanding the unexplored regulation of angiogenesis by mechanical cues may lead to the identification of novel therapeutic targets. We have recently shown that expr...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Thoppil, Roslin J., Cappelli, Holly C., Adapala, Ravi K., Kanugula, Anantha K., Paruchuri, Sailaja, Thodeti, Charles K.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041949/
https://ncbi.nlm.nih.gov/pubmed/27029071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8405
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