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Strand displacement synthesis by yeast DNA polymerase ε

DNA polymerase ε (Pol ε) is a replicative DNA polymerase with an associated 3′–5′ exonuclease activity. Here, we explored the capacity of Pol ε to perform strand displacement synthesis, a process that influences many DNA transactions in vivo. We found that Pol ε is unable to carry out extended stran...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Ganai, Rais A., Zhang, Xiao-Ping, Heyer, Wolf-Dietrich, Johansson, Erik
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041465/
https://ncbi.nlm.nih.gov/pubmed/27325747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw556
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