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Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy

Age-related loss of skeletal muscle mass and function is a major contributor to morbidity and has a profound effect on the quality of life of older people. The potential role of age-dependent mitochondrial dysfunction and cumulative oxidative stress as the underlying cause of muscle aging remains a...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Sakellariou, Giorgos K., Pearson, Timothy, Lightfoot, Adam P., Nye, Gareth A., Wells, Nicola, Giakoumaki, Ifigeneia I., Vasilaki, Aphrodite, Griffiths, Richard D., Jackson, Malcolm J., McArdle, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041117/
https://ncbi.nlm.nih.gov/pubmed/27681159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33944
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