Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle

Age-related skeletal muscle dysfunction is the underlying cause of morbidity that affects up to half the population aged 80 and over. Considerable evidence indicates that oxidative damage and mitochondrial dysfunction contribute to the sarcopenic phenotype that occurs with aging. To examine this, we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Sakellariou, Giorgos K., Pearson, Timothy, Lightfoot, Adam P., Nye, Gareth A., Wells, Nicola, Giakoumaki, Ifigeneia I., Griffiths, Richard D., McArdle, Anne, Jackson, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067250/
https://ncbi.nlm.nih.gov/pubmed/27550965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600450R
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados