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Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging

Disruption of neuromuscular junctions and denervation of some muscle fibers occurs in ageing skeletal muscle and contribute to loss of muscle mass and function. Aging is associated with mitochondrial dysfunction and loss of redox homeostasis potentially occurs through increased mitochondrial generat...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Pollock, Natalie, Staunton, Caroline A., Vasilaki, Aphrodite, McArdle, Anne, Jackson, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636617/
https://ncbi.nlm.nih.gov/pubmed/28739532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.07.017
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