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Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions

An increase in the activity of reactive oxygen species (ROS) has been implicated in the mechanisms of loss of skeletal muscle that occurs during aging, but few studies have attempted to directly assess activities in intact muscle fibers. The current project used the nonspecific fluorescent probe for...

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Autors principals: Palomero, Jesus, Vasilaki, Aphrodite, Pye, Deborah, McArdle, Anne, Jackson, Malcolm J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833391/
https://ncbi.nlm.nih.gov/pubmed/23697797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00530.2012
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