SOCS1 Mimetic Peptide Suppresses Chronic Intraocular Inflammatory Disease (Uveitis)

Uveitis is a potentially sight-threatening disease characterized by repeated cycles of remission and recurrent inflammation. The JAK/STAT pathway regulates the differentiation of pathogenic Th1 and Th17 cells that mediate uveitis. A SOCS1 mimetic peptide (SOCS1-KIR) that inhibits JAK2/STAT1 pathways...

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Spremljeno u:
Bibliografski detalji
Izdano u:Mediators Inflamm
Glavni autori: He, Chang, Yu, Cheng-Rong, Mattapallil, Mary J., Sun, Lin, Larkin III, Joseph, Egwuagu, Charles E.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040805/
https://ncbi.nlm.nih.gov/pubmed/27703302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2939370
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