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Therapeutic targeting of STAT pathways in CNS autoimmune diseases

Signal transducers and activators of transcription (STATs) transduce extracellular signals that regulate the initiation, duration and intensity of immune responses. However, unbridled activation of STATs by pro-inflammatory cytokines or growth factors contributes to pathogenic autoimmunity. In this...

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Hlavní autoři: Egwuagu, Charles E., Larkin, III, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670276/
https://ncbi.nlm.nih.gov/pubmed/24058800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.24134
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