Hepatocyte growth factor promotes proliferation, invasion, and metastasis of myeloid leukemia cells through PI3K-AKT and MAPK/ERK signaling pathway

This study aims to investigate effects of HGF expression on biological behaviors of Kasumi-1 and HL60. Expression of HGF and c-Met gene were detected using qRT-PCR. Short hairpin RNA (shRNA) was used to reduce HGF expression. Silencing effect of shRNA was verified by qRT-PCR and western blot. Cell r...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Guo, Jiang-Rui, Li, Wei, Wu, Yong, Wu, Lin-Qing, Li, Xin, Guo, Ya-Fei, Zheng, Xiao-Hui, Lian, Xiao-Lan, Huang, Hui-Fang, Chen, Yuan-Zhong
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040664/
https://ncbi.nlm.nih.gov/pubmed/27725846
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