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PTEN Regulates BCRP/ABCG2 and the Side Population through the PI3K/Akt Pathway in Chronic Myeloid Leukemia

A small population of cancer stem cells named the “side population” (SP) has been demonstrated to be responsible for the persistence of many solid tumors. However, the role of the SP in leukemic pathogenesis remains controversial. The resistance of leukemic stem cells to targeted therapies, such as...

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Detalhes bibliográficos
Main Authors: Huang, Fang-Fang, Zhang, Li, Wu, Deng-Shu, Yuan, Xiao-Yu, Chen, Fang-Ping, Zeng, Hui, Yu, Yan-Hui, Zhao, Xie-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945754/
https://ncbi.nlm.nih.gov/pubmed/24603487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088298
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