Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia

The molecular defects which lead to multistep incidences of human T-cell leukemia have yet to be identified. The DNA-binding protein Helios (known as IKZF2), a member of the Ikaros family of Krüppel-like zinc-finger proteins, functions pivotally in T-cell differentiation and activation. In this stud...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Zhao, Shaorong, Liu, Wei, Li, Yinghui, Liu, Pengjiang, Li, Shufang, Dou, Daolei, Wang, Yue, Yang, Rongcun, Xiang, Rong, Liu, Feifei
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040427/
https://ncbi.nlm.nih.gov/pubmed/27681508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163328
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы