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Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia
The molecular defects which lead to multistep incidences of human T-cell leukemia have yet to be identified. The DNA-binding protein Helios (known as IKZF2), a member of the Ikaros family of Krüppel-like zinc-finger proteins, functions pivotally in T-cell differentiation and activation. In this stud...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5040427/ https://ncbi.nlm.nih.gov/pubmed/27681508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163328 |
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