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GT198 Splice Variants Display Dominant-Negative Activities and Are Induced by Inactivating Mutations
Alternative pre-mRNA splicing yields functionally distinct splice variants in regulating normal cell differentiation as well as cancer development. The putative tumor suppressor gene GT198 (PSMC3IP), encoding a protein also known as TBPIP and Hop2, has been shown to regulate steroid hormone receptor...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743156/ https://ncbi.nlm.nih.gov/pubmed/23946869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913486345 |
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