GT198 Splice Variants Display Dominant-Negative Activities and Are Induced by Inactivating Mutations

Alternative pre-mRNA splicing yields functionally distinct splice variants in regulating normal cell differentiation as well as cancer development. The putative tumor suppressor gene GT198 (PSMC3IP), encoding a protein also known as TBPIP and Hop2, has been shown to regulate steroid hormone receptor...

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Autori principali: Peng, Min, Yang, Zheqiong, Zhang, Hao, Jaafar, Lahcen, Wang, Guanghu, Liu, Min, Flores-Rozas, Hernan, Xu, Jianming, Mivechi, Nahid F., Ko, Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2013
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743156/
https://ncbi.nlm.nih.gov/pubmed/23946869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913486345
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