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STRUM: structure-based prediction of protein stability changes upon single-point mutation
Motivation: Mutations in human genome are mainly through single nucleotide polymorphism, some of which can affect stability and function of proteins, causing human diseases. Several methods have been proposed to predict the effect of mutations on protein stability; but most require features from exp...
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Publicado no: | Bioinformatics |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5039926/ https://ncbi.nlm.nih.gov/pubmed/27318206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw361 |
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