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A three-state prediction of single point mutations on protein stability changes

BACKGROUND: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from structure. In proteomics and genomics studies prediction of protein stability free energy change (ΔΔG) upon single point mut...

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Detalhes bibliográficos
Main Authors: Capriotti, Emidio, Fariselli, Piero, Rossi, Ivan, Casadio, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323669/
https://ncbi.nlm.nih.gov/pubmed/18387208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S2-S6
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